[Summary of the ESC position paper on cancer treatment and cardiovascular toxicity].

{"article_title":"[Summary of the ESC position paper on cancer treatment and cardiovascular toxicity].","author":"Hoog J, Achenbach S","journal_title":"Herz","issn":"1615-6692","isbn":"","publication_date":"2019 May","volume":"41","issue":"8","first_page":"684","page_count":"","accession_number":"27830273","doi":"10.1007\/s00059-016-4493-6","publisher":"Urban Und Vogel","doctype":"Journal Article","subjects":"Cardiology standards; Cardiovascular Diseases diagnosis; Cardiovascular Diseases therapy; Medical Oncology standards; Neoplasms complications; Neoplasms therapy; Cardiovascular Diseases etiology; Diagnostic Techniques, Cardiovascular standards; Echocardiography standards; Europe; Evidence-Based Medicine standards; Guideline Adherence standards; Humans; Neoplasms diagnosis; Practice Guidelines as Topic; Treatment Outcome","interest_area":["Cardiology"," Oncology"," Emergency Medicine"],"abstract":"The numbers of survivors of cancer have increased as a consequence of advances in chemotherapy; however, the side effects of cancer treatment have become increasingly more important. The most frequent side effects include cardiovascular complications, which can lead to acute and delayed morbidity and mortality, often many years later. The discipline of cardio-oncology deals with the prevention, diagnostics and treatment of cardiovascular diseases caused by cancer therapy. The most important cardiovascular side effects of cytostatic therapy are heart failure due to myocardial dysfunction (cardiotoxicity), coronary artery disease, valvular disease and ventricular arrhythmia as a result of QT extension. In addition, arterial hypertension, thromboembolic events, pulmonary hypertension, vasculopathy and pericardial complications can also occur. Fundamentally, a strict limitation of risk factors is necessary to minimize the cardiovascular side effects of potentially cardiotoxic therapeutic procedures. Patients with impaired left ventricular function should be identified by echocardiographic examination prior to cardiotoxic chemotherapy. Treatment with beta blockers and angiotensin-converting enzyme (ACE) inhibitors can also be indicated in asymptomatic patients in order to minimize the effects of chemotherapy on myocardial dysfunction. Prophylactic administration of ACE inhibitors and beta blockers during anthracycline chemotherapy can be considered in patients free of cardiac disease.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=27830273&authtype=shib&custid=ns346513&group=main&profile=eds","isPdfLink":true,"isSAML":false,"additionalInfo":{"Authored_By":"Hoog J, Achenbach S","Journal_Info":"Publisher: Urban Und Vogel Country of Publication: Germany NLM ID: 7801231 Publication Model: Print Cited Medium: Internet ISSN: 1615-6692 (Electronic) Linking ISSN: 03409937 NLM ISO Abbreviation: Herz Subsets: MEDLINE","Publication_Type":"Journal Article; Practice Guideline; Review","Published_Date":"2016-12-01","Source":"Herz [Herz] 2016 Dec; Vol. 41 (8), pp. 684-689.","Languages":"German","Electronic_ISSN":"1615-6692","MeSH_Terms":"Cardiology\/*standards , Cardiovascular Diseases\/*diagnosis , Cardiovascular Diseases\/*therapy , Medical Oncology\/*standards , Neoplasms\/*complications , Neoplasms\/*therapy, Cardiovascular Diseases\/etiology ; Diagnostic Techniques, Cardiovascular\/standards ; Echocardiography\/standards ; Europe ; Evidence-Based Medicine\/standards ; Guideline Adherence\/standards ; Humans ; Neoplasms\/diagnosis ; Practice Guidelines as Topic ; Treatment Outcome","Subjects":"Cardiovascular Diseases etiology, Diagnostic Techniques, Cardiovascular standards, Echocardiography standards, Europe, Evidence-Based Medicine standards, Guideline Adherence standards, Humans, Neoplasms diagnosis, Practice Guidelines as Topic, Treatment Outcome, Cardiology standards, Cardiovascular Diseases diagnosis, Cardiovascular Diseases therapy, Medical Oncology standards, Neoplasms complications, Neoplasms therapy","Title_Abbreviations":"Herz","Volume":"41"},"header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"27830273","RelevancyScore":"816","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"815.607055664063"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=27830273&authtype=shib&custid=ns346513&group=main&profile=eds","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=27830273&authtype=shib&custid=ns346513&group=main&profile=eds"}