European Society of Endocrinology Clinical Practice Guideline: Endocrine work-up in obesity.

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Clinical Guidelines
Authored By
Pasquali R, Casanueva F, Haluzik M, van Hulsteijn L, Ledoux S, Monteiro MP, Salvador J, Santini F, Toplak H, Dekkers OM
Authored On
Interests
Endocrinology
Internal/Family Medicine
Speciality
Endocrinology
Internal/Family Medicine
Book Detail
volume
182
ISSN
1479-683X
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ISSN
1479-683X ; Electronic
IS_Ebsco
true
Additional Info
["Pasquali R, Casanueva F, Haluzik M, van Hulsteijn L, Ledoux S, Monteiro MP, Salvador J, Santini F, Toplak H, Dekkers OM","Publisher: Oxford University Press Country of Publication: England NLM ID: 9423848 Publication Model: Print Cited Medium: Internet ISSN: 1479-683X (Electronic) Linking ISSN: 08044643 NLM ISO Abbreviation: Eur J Endocrinol Subsets: MEDLINE","Journal Article; Practice Guideline","2020-01-01","European journal of endocrinology [Eur J Endocrinol] 2020 Jan; Vol. 182 (1), pp. G1-G32.","English","1479-683X","Body Mass Index*, Hypothyroidism\/*diagnosis , Obesity\/*diagnosis, Comorbidity ; Endocrinology ; Humans ; Hypothyroidism\/epidemiology ; Obesity\/epidemiology ; Prevalence ; Thyroid Function Tests","Comorbidity, Endocrinology, Humans, Hypothyroidism epidemiology, Obesity epidemiology, Prevalence, Thyroid Function Tests, Body Mass Index, Hypothyroidism diagnosis, Obesity diagnosis","European journal of endocrinology","182"]
Description
Obesity is an emerging condition, with a prevalence of ~20%. Although the simple measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and there are currently no data showing that more sophisticated methods are more useful to guide the endocrine work-up in obesity. An increased BMI leads to a number of hormonal changes. Additionally, concomitant hormonal diseases can be present in obesity and have to be properly diagnosed - which in turn might be more difficult due to alterations caused by body fatness itself. The present European Society of Endocrinology Clinical Guideline on the Endocrine Work-up in Obesity acknowledges the increased prevalence of many endocrine conditions in obesity. It is recommended to test all patients with obesity for thyroid function, given the high prevalence of hypothyroidism in obesity. For hypercortisolism, male hypogonadism and female gonadal dysfunction, hormonal testing is only recommended if case of clinical suspicion of an underlying endocrine disorder. The guideline underlines that weight loss in obesity should be emphasized as key to restoration of hormonal imbalances and that treatment and that the effect of treating endocrine disorders on weight loss is only modest.
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