Safely Doing Less for Febrile Infants: Reviewing Management in the Setting of the 2021 American Academy of Pediatrics Clinical Practice Guideline.

{"article_title":"Safely Doing Less for Febrile Infants: Reviewing Management in the Setting of the 2021 American Academy of Pediatrics Clinical Practice Guideline.","author":"\"Adler, Abigail R , Browning, Whitney L\"","journal_title":"Pediatric annals","issn":"1938-2359 ; Electronic","isbn":"","publication_date":"20240601","volume":"53","issue":"6","first_page":"e202","page_count":"","accession_number":"38852083","doi":"10.3928\/19382359-20240407-01","publisher":"Slack","doctype":"Journal Article","subjects":"Pediatrics","interest_area":["Pediatric Medicine"," Internal\/Family Medicine"],"abstract":"For more than 4 decades, pediatricians have sought the best practices for effectively managing well-appearing young febrile infants. In 2021, the American Academy of Pediatrics released a clinical practice guideline for the management of well-appearing febrile infants aged 8 to 60 days. The guideline incorporates advancements in testing, such as biomarkers and diagnostic testing in the setting of changing epidemiology, to help risk stratify infants in the newly formed group age 22 to 28 days as well as the group age 29 to 60 days. The new guideline uses inflammatory markers (procalcitonin, C-reactive protein, absolute neutrophil count, and a temperature >38.4\u00b0C) to identify infants at low risk for invasive bacterial infection who can potentially avoid the invasive procedures of lumbar puncture, hospitalization, and broad-spectrum antimicrobials. Because of continued ambiguity, incorporating shared decision-making with families in the care of these infants will be important, as will ongoing clinical research to better inform future practice. <b>[ <i>Pediatr Ann<\/i> . 2024;53(6):e202-e207.]<\/b> .","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=38852083&authtype=shib&custid=ns346513","isPdfLink":true,"isSAML":false,"additionalInfo":{"Authored_By":"Adler AR, Browning WL","Journal_Info":"Publisher: Slack Country of Publication: United States NLM ID: 0356657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-2359 (Electronic) Linking ISSN: 00904481 NLM ISO Abbreviation: Pediatr Ann Subsets: MEDLINE","Publication_Type":"Journal Article","Published_Date":"2024-06-01","Source":"Pediatric annals [Pediatr Ann] 2024 Jun; Vol. 53 (6), pp. e202-e207. Date of Electronic Publication: 2024 Jun 01.","Languages":"English","Electronic_ISSN":"1938-2359","MeSH_Terms":"Fever*\/etiology , Fever*\/diagnosis , Pediatrics*\/methods , Pediatrics*\/standards , Practice Guidelines as Topic*, Humans ; Infant ; Infant, Newborn ; Anti-Bacterial Agents\/therapeutic use ; Bacterial Infections\/diagnosis ; Bacterial Infections\/drug therapy ; Biomarkers\/blood ; Societies, Medical ; United States","Subjects":"Humans, Infant, Infant, Newborn, Anti-Bacterial Agents therapeutic use, Bacterial Infections diagnosis, Bacterial Infections drug therapy, Biomarkers blood, Societies, Medical, United States, Fever etiology, Fever diagnosis, Pediatrics methods, Pediatrics standards, Practice Guidelines as Topic","Title_Abbreviations":"Pediatric annals","Volume":"53"},"header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"38852083","RelevancyScore":"924","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"924.313354492188"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=38852083&authtype=shib&custid=ns346513&group=main&profile=eds","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=38852083&authtype=shib&custid=ns346513&group=main&profile=eds"}