Cardiovascular diseases remain the leading cause of death globally, with high mortality in low- and middle-income countries. Hypertension is a major contributor to this burden, which despite the availability of effective and affordable treatments, has lower global control rates.
This 2021 guideline from the World Health Organization (WHO) provides updated recommendations to support the initiation of pharmacological treatment for hypertension in adults. The evidence-based recommendations are intended for non-pregnant adults who have been properly diagnosed and counselled on lifestyle changes.
The guideline further outlines when to begin medication, plan appropriate treatment targets and follow-up intervals, and provides details on which healthcare providers may initiate care. Additionally, it offers guidance on treatment strategies such as monotherapy, combination therapy, and single-pill combinations.