Acid peptic disorders result from a variety of interconnected pathogenic mechanisms, all of which lead to tissue damage. Modern treatments focus on targeting these physiological pathways to effectively manage and alleviate symptoms. Among the Acid Peptic Disorders, Gastroesophageal Reflux Disease (GERD) is one of the most frequently diagnosed conditions, particularly in Western Africa, where its prevalence is reported to be between 15 to 19.9%.
Esomeprazole, the S-isomer of racemic omeprazole, has shown superior acid control compared to omeprazole and rabeprazole. Its enhanced bioavailability allows for more potent and sustained suppression of gastric acid, making it a highly effective treatment for acid-related diseases, especially GERD.
This detailed monograph explores various studies on the efficacy of Esomeprazole, emphasizing its exceptional performance in managing GERD and other acid peptic disorders. The monograph highlights its potential as a superior therapy, providing patients with significant symptom relief and improved quality of life through its strong and prolonged acid-suppressing effects.