Rosuvastatin: A Review of the Pharmacology and Clinical Effectiveness in Cardiovascular Disease

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Dermatology
Emergency Medicine
Endocrinology
ENT
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Hematology
Immunology Allergy & Inflammation
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Description

Rosuvastatin, a next-generation HMG-CoA reductase inhibitor, offers potent LDL-C lowering with minimal CYP3A4 interaction and limited extrahepatic penetration. This review highlights its pharmacology, efficacy, safety, and findings from major clinical trials in hypercholesterolemia and cardiovascular prevention, underscoring its role in modern lipid management.

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