PEARL Study Trial Overview: An Analysis of Rosuvastatin Use in Dyslipidemia Management

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Description

The PEARL Study, a first of its kind, real-world prospective observational study conducted in Nigeria, evaluated the usage patterns, safety, and efficacy of Rosuvastatin in patients with Dyslipidemia. The study included 221 patients, mostly middle-aged, who were treated with 5mg, 10mg, or 20mg doses of Rosuvastatin across three visits. Results were assessed based on:

  • Significant improvements in lipid profiles, with reductions in LDL-C, total cholesterol and triglycerides 
  • Increase in HDL 
  • Reduction in blood pressure 
  • Patient adherence to Rosuvastatin over the study duration

This overview presents these findings in detail, along with physician assessments highlighting Rosuvastatin’s safety, efficacy, and value in long-term dyslipidemia management. 

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