Description
A study found that cefixime dispersible tablets formulated with crospovidone as a superdisintegrant can deliver faster disintegration and dissolution, offering a more efficient alternative to existing marketed formulations. The choice of superdisintegrant and compression method was found to significantly influence tablet hardness and wetting time. Key findings revealed that the formulation containing 10% crospovidone (CP), exhibited favorable results—achieving a disintegration time of 25 seconds and a wetting time of 20 seconds. In addition, the formulation showed a rapid dissolution rate, reaching 80% drug release within 0.75 minutes.